Research and Development Specialist – Bioinformatician

Université du Luxembourg

Belval, Esch-sur-Alzette
Contrat
Temps-plein

Il y a 2 mois

The Luxembourg Centre for Systems Biomedicine (LCSB) is an interdisciplinary research centre of the University of Luxembourg. We conduct fundamental and translational research in the field of Systems Biology and Biomedicine – in the lab, in the clinic and in silico. We focus on neurodegeneration and are especially interested in Alzheimer’s and Parkinson’s disease and their contributing factors.The LCSB recruits talented scientists from various disciplines. Computer scientists, mathematicians, biologists, chemists, engineers, physicists and clinicians from more than 50 countries currently work at the LCSB. We excel because we are truly interdisciplinary and together, we contribute to science and society.Successful candidates will join the Bioinformatics Core, led by Prof. Reinhard Schneider, which focuses on managing and analysing complex biomedical and clinical data. We are internationally recognized for our cutting-edge data handling, analysis and mining including GDPR compliant data hosting solutions, data management systems and high performance and throughput approaches. We develop innovative methodologies for data mining, federated data analysis, and data FAIRification. We strongly advocate following responsible and reproducible research (R3) principles and best practices in software development. For more information, .We are looking for a Bioinformatician to analyse high throughput single and bulk cell RNA sequencing datasets, spatial transcriptomics and multi-omics (metabolomics and proteomics) datasets. The Bioinformatician will interact with scientific researchers, post-doctoral fellows and research technicians of the different groups at the LCSB to explore and analyze large and heterogenous datasets in the area of neurogenerative diseases, especially Parkinson’s and Alzheimer’s Diseases.Your Role...

Participate in research activities involved in the analysis of multiomics data sets including next-generation sequencing, single cell/nuclear transcriptomics, bulk RNA sequencing, spatial transcriptomics, metabolomics and proteomics datasets
Coordinate data handling and analysis for multi-omics data
Participate as a team member in experimental design and data analysis
Coordinate publications related to the project and scientific results
Work in close collaboration with LCSB members on scientific projects

What we expect from you…

Education:

Essential: Master’s degree or equivalent in bioinformatics, computational biology, medical engineering, computer science, with an interest in biomedical informatics and translational medicine
Desirable: PhD in any of the above-mentioned fields of study
Demonstrated expertise in R programming with a strong command of bioinformatics workflows, including data manipulation, statistical analysis, and visualization using relevant packages from Bioconductor including (but not limited) to DESeq2, limma, BioMart, Seurat, gViz, and edgeR
Proficiency in developing interactive web applications and data visualizations with R Shiny, Plotly, ggplot2, and Seaborn or similar dataviz libraries
Proficiency in Python
Familiarity with UNIX systems including SHELL or AWK scripting
Experience in working on High-Performance Computing (HPC) environment is an advantage
Excellent verbal and written communication skills and the ability to articulate clearly scientific and technical needs
Excellent capacity to work with others in a collaborative environment
Prior experience in analysis of bulk, single-cell/nuclear, spatial transcriptomics as well as multi-omics data is necessary and research experience in neurogenerative diseases AD/PD is considered an advantage

Here’s what awaits you at the LCSB...

Excellent work environment with state-of-the-art infrastructure, laboratory and administrative support
Truly connected. We work together with hospitals and research institutes on a national and international level as well as industrial partners. Connection between science and society is very important to us. From our school lab – the Scienteens Lab – to the different outreach activities and collaborative partnerships with patient associations, we love to listen to society’s needs and share our passion for science
Be part of a multicultural team. At the LCSB we have more than 50 nationalities. Throughout the year, we organise team-building events, networking activities and more

How to apply...Applications should be submitted online and include:

A detailed curriculum vitae (CV)
A cover letter describing your motivation to join our group, how you fit in the group and most recent work experiences
Contact information and recommendation letters from at least 3 referees

Early application is highly encouraged, as the applications will be processed upon reception. Please apply formally through the HR system. Applications by email will not be considered.The University of Luxembourg embraces inclusion and diversity as key values. We are fully committed to removing any discriminatory barrier related to gender, and not only, in recruitment and career progression of our staff.General information:

Contract type: Fixed Term Contract 36 Month (extension possible)
Work hours: Full Time 40.0 Hours per Week
Location: Belval
Internal title: Research and development specialist
Job reference: UOL06295

In return you will get…

Multilingual and international character. Modern institution with a personal atmosphere. Staff coming from 90 countries. Member of the “University of the Greater Region” (UniGR)
A modern and dynamic university. High-quality equipment. Close ties to the business world and to the Luxembourg labour market. A unique urban site with excellent infrastructure
A partner for society and industry. Cooperation with European institutions, innovative companies, the Financial Centre and with numerous non-academic partners such as ministries, local governments, associations, NGOs …

About the University of Luxembourg...University of Luxembourg is an international research university with a distinctly multilingual and interdisciplinary character. The University was founded in 2003 and has more than 6,700 students and more than 2,000 employees from around the world. The University’s faculties and interdisciplinary centres focus on research in the areas of Computer Science and ICT Security, Materials Science, European and International Law, Finance and Financial Innovation, Education, Contemporary and Digital History. In addition, the University focuses on cross-disciplinary research in the areas of Data Modelling and Simulation as well as Health and System Biomedicine. Times Higher Education ranks the University of Luxembourg #3 worldwide for its “international outlook,” #20 in the Young University Ranking 2021 and among the top 250 universities worldwide.For further information, please contact Dr. Venkata SATAGOPAM (email address: ). Use the job reference number mentioned above in the subject line of your email.[

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